--- In IMEGA-e@yahoogroups.com, "Colin Barton" <colin.sussexme@...>
wrote:


Perception versus polysomnographic assessment of sleep in CFS and
non-fatigued control subjects: results from a population-based study.

Journal: BMC Neurol. 2007 Dec 5;7(1):40 [Epub ahead of print]

Authors: Majer M [1,2], Jones JF [2], Unger ER [2], Solomon
Youngblood L [2], Decker MJ [3], Gurbaxani B [2], Heim C [1], Reeves
WC. [2]

Affiliations:
[1] Department of Psychiatry and Behavioral Sciences, Emory
University School of Medicine, Atlanta, USA
[2] Chronic Viral Diseases Branch, Centers for Disease Control &
Prevention, Atlanta, USA,
[3] Fusion Sleep, Suwanee, USA

NLM Citation: PMID: 18053240


ABSTRACT:
BACKGROUND: Complaints of unrefreshing sleep are a prominent
component of chronic fatigue syndrome (CFS); yet, polysomnographic
studies have not consistently documented sleep abnormalities in CFS
patients. We conducted this study to determine whether alterations in
objective sleep characteristics are associated with subjective
measures of poor sleep quality in persons with CFS.

METHODS: We examined the relationship between perceived sleep quality
and polysomnographic measures of nighttime and daytime sleep in 35
people with CFS and 40 non-fatigued control subjects, identified from
the general population of Wichita, Kansas and defined by empiric
criteria. Perceived sleep quality and daytime sleepiness were
assessed using clinical sleep questionnaires. Objective sleep
characteristics were assessed by nocturnal polysomnography and
daytime multiple sleep latency testing.

RESULTS: Participants with CFS reported unrefreshing sleep and
problems sleeping during the preceding month significantly more often
than did non-fatigued controls. Participants with CFS also rated
their quality of sleep during the overnight sleep study as
significantly worse than did control subjects. Control subjects
reported significantly longer sleep onset latency than latency to
fall asleep as measured by PSG and MSLT. There were no significant
differences in sleep pathology or architecture between subjects with
CFS and control subjects.

CONCLUSION: People with CFS reported sleep problems significantly
more often than control subjects. Yet, when measured these parameters
and sleep architecture did not differ between the two subject groups.
A unique finding requiring further study is that control, but not CFS
subjects, significantly over reported sleep latency suggesting CFS
subjects may have an increased appreciation of sleep behaviour that
may contribute to their perceived sleep problems.


[Note: This is an Open Access article.  The full text is
available for free in PDF at
http://www.biomedcentral.com/content/pdf/1471-2377-7-40.pdf ]

--- End forwarded message ---

--- In IMEGA-e@yahoogroups.com, "Colin Barton" <colin.sussexme@...>
wrote:


Sleep Quality Perception in the Chronic Fatigue Syndrome:
Correlations with Sleep Efficiency, Affective Symptoms and Intensity
of Fatigue.

Available in PDF at
http://www.cfids-cab.org/rc/Neu.pdf

Journal: Neuropsychobiology. 2007 Nov 6;56(1):40-46 [Epub ahead of
print]

Authors: Neu D, Mairesse O, Hoffmann G, Dris A, Lambrecht LJ,
Linkowski P, Verbanck P, Le Bon O.

Affiliation: Sleep Laboratory, University Hospital Brugmann,
Université Libre de Bruxelles, Brussels, Belgium.

NLM Citation: PMID: 17986836


Background/Aims: One of the core symptoms of the chronic fatigue
syndrome (CFS) is unrefreshing sleep and a subjective sensation of
poor sleep quality. Whether this perception can be expressed, in a
standardized questionnaire as the Pittsburgh Sleep Quality Index
(PSQI), has to our knowledge never been documented in CFS.
Furthermore, correlations of subjective fatigue, PSQI, affective
symptoms and objective parameters such as sleep efficiency are poorly
described in the literature.

Methods: Using a cross-sectional paradigm, we studied subjective
measures like PSQI, Fatigue Severity Scale scores and intensity of
affective symptoms rated by the Hamilton Depression and Anxiety
scales as well as objective sleep quality parameters measured by
polysomnography of 28 'pure' (no primary sleep and no psychiatric
disorders) CFS patients compared to age- and gender-matched healthy
controls.

Results: The PSQI showed significantly poorer subjective sleep
quality in CFS patients than in healthy controls. In contrast,
objective sleep quality parameters, like the Sleep Efficiency Index
(SEI) or the amount of slow-wave sleep did not differ significantly.
Subjective sleep quality showed a correlation trend with severity of
fatigue and was not correlated with the intensity of affective
symptoms in CFS.

Conclusion: Our findings indicate that a sleep quality misperception
exists in CFS or that potential nocturnal neurophysiological
disturbances involved in the nonrecovering sensation in CFS are not
expressed by sleep variables such as the SEI or sleep stage
distributions and proportions.

Copyright (c) 2007 S. Karger AG, Basel.

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